US STOCK
IONS Stock Analysis
US stocks · market data · technical indicators
Ionis Pharmaceuticals, Inc.
IONSUS stocksQuote delayed 15 min
10/27 上午06:45 updated
$43.42
+0.49+1.14%
Open
$43.00
High
$43.92
Low
$42.76
Volume
401.33萬
IONS price history
-4.72%Open
45.57
Latest
43.42
High
45.89
Low
42.38
Average
44.00
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Financial snapshot
IONS - Ionis Pharmaceuticals, Inc.
EPS
-3.45USD
Forward EPS
-1.15USD
P/E
--
Forward P/E
-37.88x
P/B
16.35x
ROE
-105.50%
ROA
-12.43%
Operating margin
-38.18%
Profit margin
-64.66%
Revenue growth
-40.70%
Earnings growth
--
Dividend yield
0.00%
Financial statements
| 2026-06-30 | 2026-03-31 | 2025-12-31 | 2025-09-30 | 2025-06-30 | |
|---|---|---|---|---|---|
| Revenue | $267.95M | $246.09M | $203.33M | $156.72M | $452.05M |
| Gross profit | $265.21M | $243.09M | $195.37M | $154.38M | $447.90M |
| Operating income | -$102.30M | -$117.48M | -$214.47M | -$160.17M | $139.84M |
| Net income | -$114.65M | -$92.53M | -$229.39M | -$128.61M | $123.55M |
| Basic EPS | -0.69 | -0.56 | -1.41 | -0.80 | 0.78 |
| Diluted EPS | -0.69 | -0.56 | -1.41 | -0.80 | 0.70 |
Estimates vs actuals
Next earnings
2026-11-04
EPS estimate
-0.93
Revenue estimate
$184.38M
Last surprise
+51.70%
| Date | Estimate | Actual | Surprise |
|---|---|---|---|
| 2026-11-04 | -0.93 | Not reported | — |
| 2026-07-29 | -0.88 | -0.42 | +51.70% |
| 2026-04-29 | -0.77 | -0.30 | +60.90% |
| 2026-02-25 | -1.22 | -1.15 | +5.56% |
| 2025-10-29 | -1.05 | -0.61 | +41.81% |
| 2025-07-30 | 0.16 | 0.85 | +415.06% |
| 2025-04-30 | -1.03 | -0.92 | +10.39% |
| 2025-02-19 | -0.84 | -0.43 | +49.03% |
| 2024-11-06 | -0.98 | -0.72 | +26.14% |
| 2024-08-01 | -0.76 | -0.24 | +68.59% |
| 2024-05-07 | -0.83 | -0.77 | +7.30% |
| 2024-02-21 | -0.75 | 0.12 | +115.80% |
Institutional holders
| Institution | Quarter | Value held | Portfolio weight |
|---|---|---|---|
| VANGUARD GROUP INC | 2025-12-31 | $1.3B | 0.02% |
| TWO SIGMA INVESTMENTS, LP | 2026-06-30 | $495.7M | 0.36% |
| BlackRock Inc. | 2024-06-30 | $491.9M | 0.01% |
| STATE STREET CORP | 2026-06-30 | $343.7M | 0.01% |
| RENAISSANCE TECHNOLOGIES LLC | 2026-06-30 | $44.4M | 0.06% |
| CITADEL ADVISORS LLC | 2026-06-30 | $18.7M | 0.00% |
13F quarterly filings. Reporting periods differ by institution; value and weight reflect each institution's own latest quarter.
Analyst ratings
Mean target
$84.13
Target range
$58.00 – $105.00
Implied upside
93.76%
Strong buy
9
Buy
12
Hold
4
Sell
0
Strong sell
0
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